Hb F-Xinjiang Agamma25(B7)Gly->Arg; 75(E19)Ile->Thr
ELECTROPHORESIS Hb FX moves between Hb S and Hb C at alkaline pH
IEF Not reported
CHROMATOGRAPHY Hb FX was isolated by DEAE-cellulose chromatography
STRUCTURE STUDIES Tryptic digestion of gammaX chain; separation of peptides by fin-gerprinting; amino acid analysis; sequencing
DNA ANALYSES Not reported; presumed mutation GGA->CGA at codon 25
NOTES Found in a Chinese newborn of the Han nationality; Hb FX 7.7% of total Hb; the variant is somewhat unstable
1. Hu, H. and Ma, M.; Hemoglobin, 11:465, 1987.

This material is from the book A Syllabus of Human Hemoglobin Variants (1996) by Titus H.J. Huisman, Marianne F.H. Carver, and Georgi D. Efremov, published by The Sickle Cell Anemia Foundation in Augusta, GA, USA. Copyright © 1996 by Titus H.J. Huisman. All rights reserved. Neither this work nor any part may be reproduced or transmitted in any form or by any means, electronic or mechanical, microfilming and recording, or by any information storage and retrieval systems, without written permission.