Hb P-India betadelta hybrid (beta through 87; delta from 116)
         
HEMATOLOGY Not known; carriers had nutritional anemia and an alpha-thal-2 heterozygosity
ELECTROPHORESIS Not reported
CHROMATOGRAPHY Not reported
STRUCTURE STUDIES Peptide separation; amino acid analysis
DNA ANALYSES Recombination point is located between beta codon 87 and the 8th nt of the delta gene; nearly the entire IVS-II is delta type
FUNCTION STUDIES Not reported
STABILITY Not reported
OCCURRENCE Found in an Indian family
OTHER INFORMATION Quantity in the heterozygote 23%
       
REFERENCES
1. Préhu, M-O., Préhu, C., Goossens, M., Galactéros, F., and Wajcman, H.: Blood, 83:261a (Suppl. 1), 1994.


This material is from the book A Syllabus of Human Hemoglobin Variants (1996) by Titus H.J. Huisman, Marianne F.H. Carver, and Georgi D. Efremov, published by The Sickle Cell Anemia Foundation in Augusta, GA, USA. Copyright © 1996 by Titus H.J. Huisman. All rights reserved. Neither this work nor any part may be reproduced or transmitted in any form or by any means, electronic or mechanical, microfilming and recording, or by any information storage and retrieval systems, without written permission.