Hb F-Tokyo | Ggamma34(B16)Val->Ile |
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ELECTROPHORESIS | No separation observed | ||
IEF | Not reported | ||
CHROMATOGRAPHY | Not reported | ||
CHAIN SEPARATION | GgammaX = 31.3%; Ggamma = 34.4%; Agamma = 34.4% | ||
STRUCTURE STUDIES | Isolation of GgammaX by preparative reversed phase HPLC; tryptic digestion; separation of peptides by reversed phase HPLC; amino acid analysis; sequencing | ||
DNA ANALYSES | Not reported; presumed mutation GTC->ATC at codon 34 | ||
NOTES | Found in a Japanese newborn |
REFERENCES | |||
1. | Chen, S.S., Wilson, J.B., Webber, B.B., Huisman, T.H.J., Miwa, S., and Amenomori, Y.: Hemoglobin, 9:25, 1985. |