Hb F-Poole Ggamma130(H8)Trp->Gly
ELECTROPHORESIS No separation observed at alkaline pH
IEF Not reported
STRUCTURE STUDIES Tryptic digestion of Hb FX; separation of peptides by fingerprinting; amino acid analysis; sequencing
DNA ANALYSES Not reported; presumed mutation TGG->GGG at codon 130
NOTES Found in a Black-Caucasian baby living in Poole, Dorset, England; variant is unstable; baby had hemolytic anemia
1. Lee-Potter, J.P., Deacon-Smith, R.A., Simpkiss, M.J., Kamuzora, H., and Leh-mann, H.: J. Clin. Pathol., 28:317, 1975.

This material is from the book A Syllabus of Human Hemoglobin Variants (1996) by Titus H.J. Huisman, Marianne F.H. Carver, and Georgi D. Efremov, published by The Sickle Cell Anemia Foundation in Augusta, GA, USA. Copyright © 1996 by Titus H.J. Huisman. All rights reserved. Neither this work nor any part may be reproduced or transmitted in any form or by any means, electronic or mechanical, microfilming and recording, or by any information storage and retrieval systems, without written permission.