Hb F-Marietta | Ggamma80(EF4)Asp->Asn |
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ELECTROPHORESIS | Hb FX moves slightly slower than Hb S | ||
IEF | Not reported | ||
CHROMATOGRAPHY | Hb FX elutes ahead of Hb F on a DEAE-cellulose column | ||
CHAIN SEPARATION | Not reported | ||
STRUCTURE STUDIES | Tryptic digestion of Hb FX; separation of peptides by reversed phase HPLC; amino acid analysis | ||
DNA ANALYSES | Not reported; presumed mutation GAT->AAT at codon 80 | ||
NOTES | Found in a Caucasian baby; Hb FX 12.4% of total Hb and 16.2% of total Hb F |
REFERENCES | |||
1. | Nakatsuji, T., Lam, H., Carver, J., and Huisman, T.H.J.: Hemoglobin, 6:407, 1982. |