Hb F-Macedonia-II Ggamma104(G6)Lys->Asn
ELECTROPHORESIS No separation reported at alkaline pH (Hb FX apparently takes the position of Hb A)
IEF Not data reported
CHROMATOGRAPHY No data reported
CHAIN SEPARATION GgammaX = 32.4% of total gamma; Ggamma = 32.8%; Agamma = 34.8%
DNA ANALYSES An AAG->AAC mutation at codon 104; G is part of the donor splice site of the second intron; substitution by C may not have altered splicing of the mRNA
NOTES Found in a Macedonian baby
1. Plaseska, D., Panovska-Popovska, S., Lazarevski, M., and Efremov, G.D.: Hemoglobin, 18:373, 1994.

This material is from the book A Syllabus of Human Hemoglobin Variants (1996) by Titus H.J. Huisman, Marianne F.H. Carver, and Georgi D. Efremov, published by The Sickle Cell Anemia Foundation in Augusta, GA, USA. Copyright © 1996 by Titus H.J. Huisman. All rights reserved. Neither this work nor any part may be reproduced or transmitted in any form or by any means, electronic or mechanical, microfilming and recording, or by any information storage and retrieval systems, without written permission.