Hb F-Kingston Ggamma55(D6)Met->Arg
ELECTROPHORESIS Hb FX moves between Hb S and Hb C at alkaline pH
IEF Not reported
CHROMATOGRAPHY Hb FX can be isolated by DEAE-cellulose chromatography
STRUCTURE STUDIES Tryptic digestion of gammaX chain; separation of peptides by reversed phase HPLC; amino acid analysis
DNA ANALYSES Not reported; presumed mutation ATG->AGG at codon 55
NOTES Found in a Jamaican baby and a Spanish baby; Hb FX 21% of total Hb
1. Serjeant, G.R., Serjeant, B.E., Lehmann, H., Dukes, M., and Robb, L.: FEBS Lett., 150:77, 1982.
2. de Pablos, J.Ma., Wilson, J.B., Kutlar, A., Kutlar, F., Webber, B.B., and Huisman, T.H.J.: Hemoglobin, 11:513, 1987.

This material is from the book A Syllabus of Human Hemoglobin Variants (1996) by Titus H.J. Huisman, Marianne F.H. Carver, and Georgi D. Efremov, published by The Sickle Cell Anemia Foundation in Augusta, GA, USA. Copyright © 1996 by Titus H.J. Huisman. All rights reserved. Neither this work nor any part may be reproduced or transmitted in any form or by any means, electronic or mechanical, microfilming and recording, or by any information storage and retrieval systems, without written permission.