Hb A2-Wrens delta98(FG5)Val->Met
CONTACT Internal; heme to alpha2beta1 contacts
ELECTROPHORESIS No separation observed
IEF No separation observed
CHROMATOGRAPHY No separation observed
DNA ANALYSIS A GTG->ATG mutation at codon 98
NOTES Found in a Black family; variant is unstable and occurred in association with HPFH
1. Codrington, J.F., Kutlar, F., Harris, H.F., Wilson, J.B., Stoming, T.A., and Huisman, T.H.J.: Biochim. Biophys. Acta, 1009:87, 1989.

This material is from the book A Syllabus of Human Hemoglobin Variants (1996) by Titus H.J. Huisman, Marianne F.H. Carver, and Georgi D. Efremov, published by The Sickle Cell Anemia Foundation in Augusta, GA, USA. Copyright © 1996 by Titus H.J. Huisman. All rights reserved. Neither this work nor any part may be reproduced or transmitted in any form or by any means, electronic or mechanical, microfilming and recording, or by any information storage and retrieval systems, without written permission.