Hb A2-Victoria delta24(B6)Gly->Asp
         
CONTACT Internal
ELECTROPHORESIS Hb X moves with Hb S at alkaline pH
IEF Not reported
CHROMATOGRAPHY Hb X was isolated by DEAE-Sephadex chromatography
STRUCTURE ANALYSIS Tryptic digestion of Hb X; separation of peptides by fingerprinting; amino acid analysis; sequencing
DNA ANALYSIS Not reported; presumed mutation GGT->GAT at codon 24
NOTES Found in members of an Iraqi family; in association with beta-thal
       
REFERENCES
1. Brennan, S.O., Williamson, D., Smith, M.B., Cauchi, M.N., MacPhee, A., and Carrell, R.W.: Hemoglobin, 8:163, 1984.


This material is from the book A Syllabus of Human Hemoglobin Variants (1996) by Titus H.J. Huisman, Marianne F.H. Carver, and Georgi D. Efremov, published by The Sickle Cell Anemia Foundation in Augusta, GA, USA. Copyright © 1996 by Titus H.J. Huisman. All rights reserved. Neither this work nor any part may be reproduced or transmitted in any form or by any means, electronic or mechanical, microfilming and recording, or by any information storage and retrieval systems, without written permission.