Hb A2-Adria delta51(D2)Pro->Arg
CONTACT alpha1beta2 contact
ELECTROPHORESIS Hb X moves slower than Hb A2
IEF Not reported
CHROMATOGRAPHY Hb X was isolated by DEAE-Sephadex chromatography
STRUCTURE ANALYSIS Tryptic digestion of Hb X; separation of peptides by fingerprinting; amino acid analysis
DNA ANALYSIS Not reported; presumed mutation CCT->CGT at codon 51
NOTES Found in members of an Italian family; occurred in association with beta-thal
1. Alberti, R., Tentori, L., Marinucci, M., and Borghesi, V.: Hemoglobin, 2:171, 1978.

This material is from the book A Syllabus of Human Hemoglobin Variants (1996) by Titus H.J. Huisman, Marianne F.H. Carver, and Georgi D. Efremov, published by The Sickle Cell Anemia Foundation in Augusta, GA, USA. Copyright © 1996 by Titus H.J. Huisman. All rights reserved. Neither this work nor any part may be reproduced or transmitted in any form or by any means, electronic or mechanical, microfilming and recording, or by any information storage and retrieval systems, without written permission.