Hb Takamatsu beta120(GH3)Lys->Gln
CONTACT External
HEMATOLOGY Normal in the heterozygote
ELECTROPHORESIS Hb X moves faster than Hb A at alkaline pH
STRUCTURE STUDIES Tryptic digestion of AE-betaX chain; separation of peptides by fingerprinting; amino acid analysis; sequencing
DNA ANALYSES Not reported; presumed mutation AAA->CAA at codon 120
FUNCTION STUDIES Normal oxygen affinity
OCCURRENCE Found in three unrelated Japanese families
OTHER INFORMATION Quantity in the heterozygote 48%
1. Iuchi, I., Hidaka, K., Harano, T., Ueda, S., Shibata, S., Shimasaki, S., Mizushima, J., Kubo, N., Miyake, T., and Uchida, T.: Hemoglobin, 4:165, 1980.

This material is from the book A Syllabus of Human Hemoglobin Variants (1996) by Titus H.J. Huisman, Marianne F.H. Carver, and Georgi D. Efremov, published by The Sickle Cell Anemia Foundation in Augusta, GA, USA. Copyright © 1996 by Titus H.J. Huisman. All rights reserved. Neither this work nor any part may be reproduced or transmitted in any form or by any means, electronic or mechanical, microfilming and recording, or by any information storage and retrieval systems, without written permission.