Hb Sarrebourg | beta131(H9)Gln->Arg |
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CONTACT | Internal; alpha1beta1 contact | ||
HEMATOLOGY | Iron-deficiency anemia in the carrier | ||
ELECTROPHORESIS | Hb X and Hb A separate at alkaline pH; Hb X moves like Hb F, and between Hb F and Hb S on IEF | ||
CHROMATOGRAPHY | Not reported | ||
STRUCTURE STUDIES | Not reported in detail; only final data are presented | ||
DNA ANALYSES | Not reported; presumed mutation CAG->CGG at codon 131 | ||
FUNCTION STUDIES | Normal | ||
STABILITY | Unstable | ||
OCCURRENCE | Found in a 9-year-old Turkish boy | ||
OTHER INFORMATION | Hb X comprised ~30% of the total Hb |
REFERENCES | |||
1. | Duwig, I., North, M.L., Barth, J.G., Rieffel, M., Nierengarten, P., Arous, N., Riou, J., and Galacteros, F.: Abstract, Nouv. Rev. Fr. d'Hematol., 29:344, 1987. |