Hb J-Taichung | beta129(H7)Ala->Asp |
---|
CONTACT | Internal | ||
HEMATOLOGY | Normal in the heterozygote | ||
ELECTROPHORESIS | Hb X and Hb A separate at alkaline pH; Hb X moves ahead of Hb A | ||
CHROMATOGRAPHY | Hb X was isolated by DEAE-Sephadex chromatography | ||
STRUCTURE STUDIES | Tryptic digestion; separation of peptides by fingerprinting; amino acid analysis | ||
DNA ANALYSES | Not reported; presumed mutation GCC->GAC at codon 129 | ||
FUNCTION STUDIES | Not reported | ||
STABILITY | Not reported | ||
OCCURRENCE | Found in a 14-year-old Chinese female | ||
OTHER INFORMATION | Quantity in the heterozygote 41% |
REFERENCES | |||
1. | Blackwell, R.Q., Yang, H-J., and Wang, C-C.: Biochim. Biophys. Acta, 194:1, 1969. |