Hb J-Kaohsiung beta59(E3)Lys->Thr
CONTACT External
HEMATOLOGY Not reported
ELECTROPHORESIS Hb X and Hb A separate at alkaline pH (Hb X is fast moving) but not at acidic pH
CHROMATOGRAPHY Hb X was isolated on a DEAE-Sephadex column
STRUCTURE STUDIES Tryptic digestion; separation of peptides by fingerprinting; amino acid analysis; CNBr; carboxypeptidase B digestion for C-terminal determination
DNA ANALYSES Not reported; presumed mutation AAG->ACG at codon 59
STABILITY Not reported
OCCURRENCE Found in a few Chinese families
OTHER INFORMATION Quantity in the heterozygote 47%
1. Blackwell, R.Q., Liu, C-S., and Shih, T-B.: Biochim. Biophys. Acta, 229:343, 1971.
2. Shih, T-B.: Vox Sang., 22:469, 1972.

This material is from the book A Syllabus of Human Hemoglobin Variants (1996) by Titus H.J. Huisman, Marianne F.H. Carver, and Georgi D. Efremov, published by The Sickle Cell Anemia Foundation in Augusta, GA, USA. Copyright © 1996 by Titus H.J. Huisman. All rights reserved. Neither this work nor any part may be reproduced or transmitted in any form or by any means, electronic or mechanical, microfilming and recording, or by any information storage and retrieval systems, without written permission.