Hb Henri Mondor beta26(B8)Glu->Val
CONTACT External
HEMATOLOGY Mild hypochromic microcytic anemia in the heterozygote
ELECTROPHORESIS Hb X and Hb A2 can be separated at alkaline pH; Hb X moves between Hb F and Hb S
CHROMATOGRAPHY Hb X was isolated by DEAE-Sephadex chromatography
STRUCTURE STUDIES Tryptic digestion; fingerprinting; cation exchange chromatography; amino acid analysis; sequencing
DNA ANALYSES Not reported; presumed mutation GAG->GTG at codon 26
STABILITY Slightly unstable
OCCURRENCE Found in a 9-year-old African female
OTHER INFORMATION Quantity in the heterozygote 37.5%
1. Blouquit, Y., Arous, N., Machado, P.E.A., and Garel, M.C.: FEBS Lett., 72:5, 1976.

This material is from the book A Syllabus of Human Hemoglobin Variants (1996) by Titus H.J. Huisman, Marianne F.H. Carver, and Georgi D. Efremov, published by The Sickle Cell Anemia Foundation in Augusta, GA, USA. Copyright © 1996 by Titus H.J. Huisman. All rights reserved. Neither this work nor any part may be reproduced or transmitted in any form or by any means, electronic or mechanical, microfilming and recording, or by any information storage and retrieval systems, without written permission.