Hb Christchurch beta71(E15)Phe->Ser
         
CONTACT Heme contact
HEMATOLOGY Heinz body hemolytic anemia in the heterozygote
ELECTROPHORESIS Hb X moves with Hb A on various media at various pH values
CHROMATOGRAPHY Not reported
STRUCTURE STUDIES 14C-labeled hydrolysate; fingerprinting; chymotrypsin; amino acid analysis; autoradiographs
DNA ANALYSES Not reported; presumed mutation TTT->TCT at codon 71
FUNCTION STUDIES Not reported
STABILITY Unstable
OCCURRENCE Found in an 18-year-old female living in Australia
OTHER INFORMATION Quantity in the heterozygote about 22%
       
REFERENCES
1. Carrell, R.W. and Owen, M.C.: Biochim. Biophys. Acta, 236:507, 1971.


This material is from the book A Syllabus of Human Hemoglobin Variants (1996) by Titus H.J. Huisman, Marianne F.H. Carver, and Georgi D. Efremov, published by The Sickle Cell Anemia Foundation in Augusta, GA, USA. Copyright © 1996 by Titus H.J. Huisman. All rights reserved. Neither this work nor any part may be reproduced or transmitted in any form or by any means, electronic or mechanical, microfilming and recording, or by any information storage and retrieval systems, without written permission.