Hb Avicenna beta47(CD6)Asp->Ala
CONTACT External
HEMATOLOGY Normal in the heterozygote
ELECTROPHORESIS Hb X and Hb A separate at both alkaline and acidic pH; Hb X moves like Hb S at pH 8.5 and 6.2
CHROMATOGRAPHY Hb X was isolated by DEAE-cellulose chromatography
STRUCTURE STUDIES Tryptic digestion; fingerprinting; amino acid analysis; thermolytic digestion
DNA ANALYSES Not reported; presumed mutation GAT->GCT at codon 47
OCCURRENCE Found in a young Iranian male
OTHER INFORMATION Quantity in the heterozygote 40%
1. Rahbar, S., Nozari, G., and Ala, F.: Biochim. Biophys. Acta, 576:466, 1979.

This material is from the book A Syllabus of Human Hemoglobin Variants (1996) by Titus H.J. Huisman, Marianne F.H. Carver, and Georgi D. Efremov, published by The Sickle Cell Anemia Foundation in Augusta, GA, USA. Copyright © 1996 by Titus H.J. Huisman. All rights reserved. Neither this work nor any part may be reproduced or transmitted in any form or by any means, electronic or mechanical, microfilming and recording, or by any information storage and retrieval systems, without written permission.