Hb Perspolis | alpha64(E13)Asp->Tyr |
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CONTACT | External | ||
HEMATOLOGY | Normal in the heterozygote | ||
ELECTROPHORESIS | Hb X and Hb A separate at alkaline and acidic pH; Hb X moves slightly faster than Hb D on cellulose acetate and starch gel | ||
CHROMATOGRAPHY | Hb X can be isolated on a DEAE-Sephadex column | ||
STRUCTURE STUDIES | Tryptic digestion; separation of peptides by fingerprinting; amino acid analysis; sequencing | ||
DNA ANALYSES | Not reported; presumed mutation GAC->TAC; alpha2 or alpha1 | ||
FUNCTIONAL STUDIES | Not reported | ||
STABILITY | Not reported | ||
OCCURRENCE | Found in an Indian Sikh | ||
OTHER INFORMATION | Quantity in the heterozygote 20% |
REFERENCES | |||
1. | Rahbar, S., Ala, F., Akhavan, E., Nowzari, G., Shoa'l, I., and Zamanianpoor, M.H.: Biochim. Biophys. Acta, 427:119, 1976. |