Hb GuiZhou	alpha77(EF6)Pro->Arg

CONTACT		External
HEMATOLOGY		Normal in the heterozygote
ELECTROPHORESIS		Hb X has a mobility like Hb G on cellulose acetate at alkaline pH
CHROMATOGRAPHY		Not reported
STRUCTURE STUDIES		Separation of tryptic peptides by reversed phase HPLC; amino acid analysis
DNA ANALYSES		Not reported; presumed mutation CCC->CGC; alpha2 or alpha1
FUNCTIONAL STUDIES		Not reported
STABILITY		Normal
OCCURRENCE		Found in a 47-year-old Chinese woman of the Miao ethnic group and four members of her family
OTHER INFORMATION		Quantity in the heterozygote ~25%

REFERENCES
1.		Chih-chuan, L., Fei, X., Kegong, Y., Songsen, C., Peichen, J., Maoqi, Z., and Zhiheng, Z.: Hemoglobin, 8:387, 1984.

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This material is from the book A Syllabus of Human Hemoglobin Variants (1996) by Titus H.J. Huisman, Marianne F.H. Carver, and Georgi D. Efremov, published by The Sickle Cell Anemia Foundation in Augusta, GA, USA. Copyright © 1996 by Titus H.J. Huisman. All rights reserved. Neither this work nor any part may be reproduced or transmitted in any form or by any means, electronic or mechanical, microfilming and recording, or by any information storage and retrieval systems, without written permission.