Hb Atago alpha85(F6)Asp->Tyr
CONTACT External
HEMATOLOGY Not reported
ELECTROPHORESIS Hb X moves slower than Hb F on starch gel at alkaline pH
CHROMATOGRAPHY The variant was isolated on a CM-cellulose column
STRUCTURE STUDIES Tryptic digestion; separation of peptides by fingerprinting; amino acid analysis
DNA ANALYSES Not reported; presumed mutation GAC->TAC; alpha2 or alpha1
FUNCTIONAL STUDIES Increased oxygen affinity
STABILITY Not reported
OCCURRENCE Found in a Japanese female
OTHER INFORMATION Quantity in the heterozygote 22-24%
1. Fujiwara, N., Maekawa, T., and Matsuda, G.: Int. J. Prot. Res., 3:35, 1971.

This material is from the book A Syllabus of Human Hemoglobin Variants (1996) by Titus H.J. Huisman, Marianne F.H. Carver, and Georgi D. Efremov, published by The Sickle Cell Anemia Foundation in Augusta, GA, USA. Copyright © 1996 by Titus H.J. Huisman. All rights reserved. Neither this work nor any part may be reproduced or transmitted in any form or by any means, electronic or mechanical, microfilming and recording, or by any information storage and retrieval systems, without written permission.