Hb F-Kuala Lumpur Agamma22(B4)Asp->Gly
ELECTROPHORESIS Hb FX moves between Hb S and Hb C at alkaline pH
IEF Not reported
CHROMATOGRAPHY Hb FX and Hb A cannot be separated by DEAE-Sephadex chromatography
STRUCTURE STUDIES Tryptic digestion of AE-gammaX chain; separation of peptides by fingerprinting; amino acid analysis
DNA ANALYSES Not reported; presumed mutation GAT->GGT at codon 22
NOTES Found in a Few Indian newborn babies; Hb FX 11% of total Hb
1. Lie-Injo, L.E., Wiltshire, B.G., and Lehmann, H.: Biochim. Biophys. Acta, 322:224, 1973.

This material is from the book A Syllabus of Human Hemoglobin Variants (1996) by Titus H.J. Huisman, Marianne F.H. Carver, and Georgi D. Efremov, published by The Sickle Cell Anemia Foundation in Augusta, GA, USA. Copyright © 1996 by Titus H.J. Huisman. All rights reserved. Neither this work nor any part may be reproduced or transmitted in any form or by any means, electronic or mechanical, microfilming and recording, or by any information storage and retrieval systems, without written permission.