Hb F-Bonaire-GA | Agamma39(C5)Gln->Arg |
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ELECTROPHORESIS | Hb FX moves between Hb S and Hb C at alkaline pH | ||
IEF | Not reported | ||
CHROMATOGRAPHY | Hb FX readily separates from Hb F and Hb A by DEAE-cellulose chromatography | ||
CHAIN SEPARATION | Not reported | ||
STRUCTURE STUDIES | Tryptic digestion of gamma-FX chain; separation of peptides by reversed phase HPLC; amino acid analysis; sequencing | ||
DNA ANALYSES | Not reported; presumed mutation CAG->CGG at codon 39 | ||
NOTES | Found in a Caucasian-Vietnamese baby; Hb FX 8.3% of total Hb or 9.8% of total Hb F |
REFERENCES | |||
1. | Nakatsuji, T., Headlee, M., Lam, H., Wilson, J.B., and Huisman, T.H.J.: Hemoglobin, 6:599, 1982. |