TABLE II.   Beta-Thalassemia Mutations Occurring in Specific Populations With a High Frequency

Allele Populations Allele Populations
-88, C->T American Blacks IVS-I-5, G->C Indian; Thai; Malay; Middle East
-31, A->G Japanese IVS-I-6, T->C Italian; Greek; Balkan; West European (Portugal)
-29, A->G American Blacks IVS-I-110, G->A Italian; Greek; Cypriot; Balkan; Israeli; Lebanese; North African; West European
-28, A->G Chinese; Thai; Israeli Codon 39, C->T Italian; Greek; Balkan; North African; Israeli; West European; Middle East
Codon 6, -A North African Codons 41/42, -TTCT Chinese; Thai; Indian; Malay
Codon 8, -AA Middle East Codon 44, -C Israeli; Middle East
Codons 8/9, +G Indian; Middle East Codon 90, G->T Japanese
Codon 17, A->T Chinese; Thai IVS-II-1, G->A Israeli; Middle East; Japanese; Turkish
Codon 19, A->G Thai IVS-II-654, C->T Chinese; Thai; Japanese
IVS-I-1, G->A North African; Italian; Greek; Balkan; West European IVS-II-745, C->G Italian; Greek; Turkish
IVS-I-1, G->T Indian; Thai 619 bp deletion Indian; Pakistani; Baluchi

This material is from the book A Syllabus of Thalassemia Mutations (1997) by Titus H.J. Huisman, Marianne F.H. Carver, and Erol Baysal, published by The Sickle Cell Anemia Foundation in Augusta, GA, USA. Copyright © 1997 by Titus H.J. Huisman. All rights reserved. Neither this work nor any part may be reproduced or transmitted in any form or by any means, electronic or mechanical, microfilming and recording, or by any information storage and retrieval systems, without permission in writing from the Author.