TYPE | HPFH-6; Vietnamese (see Fig. 13) | ||
---|---|---|---|
CAUSE | A 30 kb deletion with a 5' breakpoint which is ~3.5 kb 5' to the delta gene and a 3' breakpoint that is ~8 kb 3' to the breakpoint found in HPFH-3 and close to that of the German and Belgian Ggamma(Agammadeltabeta)-thalassemia types. | ||
DETECTION | By gene mapping with different probes and primers. | ||
PHENOTYPE | |||
DISTRIBUTION | Found in two Vietnamese families. |
REFERENCES | |||
1. | Motum, P.I., Hamilton, T.J., Lindeman, R., Le, H., and Trent, R.J.: Hum. Mutat., 2:179, 1993. |