Hb F-Alexandra gamma12(A9)Thr->Lys
ELECTROPHORESIS Hb FX moves between Hb S and Hb C at alkaline pH
IEF Not reported
CHROMATOGRAPHY Hb FX was isolated by CM-Sephadex chromatography
STRUCTURE STUDIES Tryptic digestion of Hb FX; separation of peptides by fingerprinting; amino acid analysis
DNA ANALYSES Not reported; presumed mutation ACA->AAA at codon 12
NOTES Found in Greek and Swiss newborn babies
1. Vella, F., Ager, J.A.M., and Lehmann, H.: Nature, 183:30, 1959.
2. Loukopoulos, D., Kaltsoya, A., and Fessas, Ph.: Blood, 33:114, 1969.

This material is from the book A Syllabus of Human Hemoglobin Variants (1996) by Titus H.J. Huisman, Marianne F.H. Carver, and Georgi D. Efremov, published by The Sickle Cell Anemia Foundation in Augusta, GA, USA. Copyright © 1996 by Titus H.J. Huisman. All rights reserved. Neither this work nor any part may be reproduced or transmitted in any form or by any means, electronic or mechanical, microfilming and recording, or by any information storage and retrieval systems, without written permission.