Hb Atlanta-Coventry beta75(E19)Leu->Pro;
NOTE: This interesting variant was misidentified and corrected late by the same group of investigators; the leucine residue at position beta141 is not deleted but (partially) oxidized to hydroxyleucine; the same phenomenon has been observed for other Hb Atlanta heterozygotes
1. Brennan, S.O., Williamson, D., Symmans, W.A., and Carrell, R.W.: Hemoglobin, 10:225, 1986.
2. Brennan, S.O., Shaw, J., Allen, J., and George, P.M.: Br. J. Haematol., 81:99, 1992.
3. Brennan, S.O. Shaw, J.G., George, P.M., and Huisman, T.H.J.: Hemoglobin, 17:1, 1993.

This material is from the book A Syllabus of Human Hemoglobin Variants (1996) by Titus H.J. Huisman, Marianne F.H. Carver, and Georgi D. Efremov, published by The Sickle Cell Anemia Foundation in Augusta, GA, USA. Copyright © 1996 by Titus H.J. Huisman. All rights reserved. Neither this work nor any part may be reproduced or transmitted in any form or by any means, electronic or mechanical, microfilming and recording, or by any information storage and retrieval systems, without written permission.