Hb F-Urumqi Ggamma22(B4)Asp->Gly
         
ELECTROPHORESIS Hb FX moves between Hb S and Hb C at alkaline pH
IEF Not reported
CHROMATOGRAPHY Not reported
CHAIN SEPARATION Not reported
STRUCTURE STUDIES Tryptic digestion of gammaX chain; separation of peptides by fingerprinting; amino acid analysis; sequencing
DNA ANALYSES Not reported; presumed mutation GAT->GGT at codon 22
NOTES Found in a Chinese newborn (Uygur parentage); Hb FX 21.5% of total Hb
       
REFERENCES
1. Hu, H. and Ma, M.: Hemoglobin, 10:15, 1986.


This material is from the book A Syllabus of Human Hemoglobin Variants (1996) by Titus H.J. Huisman, Marianne F.H. Carver, and Georgi D. Efremov, published by The Sickle Cell Anemia Foundation in Augusta, GA, USA. Copyright © 1996 by Titus H.J. Huisman. All rights reserved. Neither this work nor any part may be reproduced or transmitted in any form or by any means, electronic or mechanical, microfilming and recording, or by any information storage and retrieval systems, without written permission.