Hb F-Marietta Ggamma80(EF4)Asp->Asn
ELECTROPHORESIS Hb FX moves slightly slower than Hb S
IEF Not reported
CHROMATOGRAPHY Hb FX elutes ahead of Hb F on a DEAE-cellulose column
STRUCTURE STUDIES Tryptic digestion of Hb FX; separation of peptides by reversed phase HPLC; amino acid analysis
DNA ANALYSES Not reported; presumed mutation GAT->AAT at codon 80
NOTES Found in a Caucasian baby; Hb FX 12.4% of total Hb and 16.2% of total Hb F
1. Nakatsuji, T., Lam, H., Carver, J., and Huisman, T.H.J.: Hemoglobin, 6:407, 1982.

This material is from the book A Syllabus of Human Hemoglobin Variants (1996) by Titus H.J. Huisman, Marianne F.H. Carver, and Georgi D. Efremov, published by The Sickle Cell Anemia Foundation in Augusta, GA, USA. Copyright © 1996 by Titus H.J. Huisman. All rights reserved. Neither this work nor any part may be reproduced or transmitted in any form or by any means, electronic or mechanical, microfilming and recording, or by any information storage and retrieval systems, without written permission.