Hb A2-Yokoshima delta25(B7)Gly->Asp
CONTACT External
IEF Hb X focuses between Hb A and Hb A2
CHROMATOGRAPHY Hb X was isolated by anion exchange HPLC
STRUCTURE ANALYSIS Tryptic digestion of deltaX chain; separation of peptides by reversed phase HPLC; amino acid analysis; sequencing
DNA ANALYSIS Not reported; presumed mutation GGT->GAT at codon 25
NOTES Found in a Japanese family; one member is a homozygote
1. Ohba, Y., Igarashi, M., Tsukahara, M., Nakashima, M., Sanada, C., Ami, M., Arai, Y., and Miyaji, T.: Hemoglobin, 9:613, 1985.

This material is from the book A Syllabus of Human Hemoglobin Variants (1996) by Titus H.J. Huisman, Marianne F.H. Carver, and Georgi D. Efremov, published by The Sickle Cell Anemia Foundation in Augusta, GA, USA. Copyright © 1996 by Titus H.J. Huisman. All rights reserved. Neither this work nor any part may be reproduced or transmitted in any form or by any means, electronic or mechanical, microfilming and recording, or by any information storage and retrieval systems, without written permission.