Hb Zengcheng beta114(G16)Leu->Met
CONTACT Internal
HEMATOLOGY Normal in the newborn
ELECTROPHORESIS IEF detected a slightly faster moving beta chain variant
CHROMATOGRAPHY The betaX and betaA chains can be separated by reversed phase HPLC
STRUCTURE STUDIES The betaX chain was aminoethylated, digested with trypsin, and the resulting peptides separated by reversed phase HPLC; amino acid analysis; sequencing
DNA ANALYSES Not reported; presumed mutation CTG->ATG at codon 114
STABILITY Not reported
OCCURRENCE Discovered in a Chinese baby from Zengcheng, PR China; parents were not available for study
1. Plaseska, D., Wilson, J.B., Gu, L-H., Kutlar, F., Huisman, T.H.J., Zeng, Y-T., and Shen, M.: Hemoglobin, 14:555, 1990.

This material is from the book A Syllabus of Human Hemoglobin Variants (1996) by Titus H.J. Huisman, Marianne F.H. Carver, and Georgi D. Efremov, published by The Sickle Cell Anemia Foundation in Augusta, GA, USA. Copyright © 1996 by Titus H.J. Huisman. All rights reserved. Neither this work nor any part may be reproduced or transmitted in any form or by any means, electronic or mechanical, microfilming and recording, or by any information storage and retrieval systems, without written permission.