Hb Nagasaki beta17(A14)Lys->Glu
CONTACT External
HEMATOLOGY Not reported
ELECTROPHORESIS Hb X moves faster than Hb A on starch gel at alkaline pH
CHROMATOGRAPHY Hb X was isolated by CM-cellulose chromatography
STRUCTURE STUDIES Tryptic digestion; fingerprinting; amino acid analysis
DNA ANALYSES Not reported; presumed mutation AAG->GAG at codon 17
STABILITY Not reported
OCCURRENCE Found in three members of a Japanese family living in Nagasaki, Japan
OTHER INFORMATION Quantity in the heterozygote 30%; heterozygotes appear to be clinically normal
1. Maekawa, M., Maekawa, T., Fujiwara, N., Tabara, K., and Matsuda, G.: Int. J. Prot. Res., II:147, 1970.

This material is from the book A Syllabus of Human Hemoglobin Variants (1996) by Titus H.J. Huisman, Marianne F.H. Carver, and Georgi D. Efremov, published by The Sickle Cell Anemia Foundation in Augusta, GA, USA. Copyright © 1996 by Titus H.J. Huisman. All rights reserved. Neither this work nor any part may be reproduced or transmitted in any form or by any means, electronic or mechanical, microfilming and recording, or by any information storage and retrieval systems, without written permission.