Hb Denver beta41(C7)Phe->Ser
CONTACT Heme contact
HEMATOLOGY Normal to mild anemia in the heterozygote; cyanosis
ELECTROPHORESIS No separation obtained at alkaline pH or by IEF
CHROMATOGRAPHY No separation reported
STRUCTURE STUDIES No details reported
DNA ANALYSES Not reported; presumed mutation TTC->TCC at codon 41
FUNCTION STUDIES Decreased oxygen affinity
OCCURRENCE Found in members of a Caucasian family
OTHER INFORMATION None; quantity in the heterozygote not determined
1. Stabler, S., Jones, R.T., Head, C, Shih, D.T.B., and Fairbanks, V.F.: Blood, 82: 229a (Suppl. 1), 1993.

This material is from the book A Syllabus of Human Hemoglobin Variants (1996) by Titus H.J. Huisman, Marianne F.H. Carver, and Georgi D. Efremov, published by The Sickle Cell Anemia Foundation in Augusta, GA, USA. Copyright © 1996 by Titus H.J. Huisman. All rights reserved. Neither this work nor any part may be reproduced or transmitted in any form or by any means, electronic or mechanical, microfilming and recording, or by any information storage and retrieval systems, without written permission.