Hb D-Bushman | beta16(A13)Gly->Arg |
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CONTACT | External | ||
HEMATOLOGY | Probably normal in the heterozygote | ||
ELECTROPHORESIS | Hb X moves to the position of Hb S on starch block at alkaline pH | ||
CHROMATOGRAPHY | Not reported | ||
STRUCTURE STUDIES | Tryptic digestion; fingerprinting; amino acid analysis | ||
DNA ANALYSES | Not reported; presumed mutation GGC->CGC at codon 16 | ||
FUNCTION STUDIES | Not reported | ||
STABILITY | Not reported | ||
OCCURRENCE | Found in members of a Kalahari Bushman family | ||
OTHER INFORMATION | Quantity in heterozygotes 34-39% |
REFERENCES | |||
1. | Wade, P.T., Jenkins, T., and Huehns, E.R.: Nature, 216:688, 1967. |