Hb Thailand alpha56(E5)Lys->Thr
         
CONTACT External; crevice
HEMATOLOGY Normal in the heterozygote
ELECTROPHORESIS Hb X moves ahead of Hb A on starch gel at alkaline pH
CHROMATOGRAPHY Not reported
STRUCTURE STUDIES Tryptic digestion; separation of peptides by fingerprinting; amino acid analysis
DNA ANALYSES Not reported; presumed mutation AAG->ACG; alpha2 or alpha1
FUNCTIONAL STUDIES Normal oxygen affinity
STABILITY Not reported
OCCURRENCE Found in a 32-year-old Thai male blood donor
OTHER INFORMATION Quantity in the heterozygote 28%
       
REFERENCES
1. Pootrakul, S., Boonyarat, D., Kematorn, B., Suanpan, S., and Wasi, P.: Hemoglobin, 1:781, 1977.


This material is from the book A Syllabus of Human Hemoglobin Variants (1996) by Titus H.J. Huisman, Marianne F.H. Carver, and Georgi D. Efremov, published by The Sickle Cell Anemia Foundation in Augusta, GA, USA. Copyright © 1996 by Titus H.J. Huisman. All rights reserved. Neither this work nor any part may be reproduced or transmitted in any form or by any means, electronic or mechanical, microfilming and recording, or by any information storage and retrieval systems, without written permission.