Hb Beijing | alpha16(A14)Lys->Asn |
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CONTACT | External | ||
HEMATOLOGY | Normal in the heterozygote | ||
ELECTROPHORESIS | Hb X moves ahead of Hb A at alkaline pH; it moves between Hb A and Hb H, probably at position of Hb J on cellulose acetate (pH 8.6) | ||
CHROMATOGRAPHY | Not reported | ||
STRUCTURE STUDIES | Tryptic digestion; separation of peptides by fingerprinting; amino acid analysis; sequencing of selected peptides | ||
DNA ANALYSES | Not reported; presumed mutation AAG->AAC or AAT; alpha2 or alpha1 | ||
FUNCTIONAL STUDIES | Not reported | ||
STABILITY | Normal | ||
OCCURRENCE | Found in a Chinese family | ||
OTHER INFORMATION | Quantity in heterozygotes 19.3% |
REFERENCES | |||
1. | Liang, C.C., Chen, S., Yang, K., Jia, P., Ma, Y., Li, T., Ni, X., Wang, X., Deng, Q., and Yao, S.: Hemoglobin, 6:629, 1982. |