Hb Albany-Suma	alpha11(A9)Lys->Asn

CONTACT		External
HEMATOLOGY		Normal in the heterozygote
ELECTROPHORESIS		Hb X moves to the position of Hb J on starch gel (pH 9.0) and cellulose acetate (pH 8.9); it moves with Hb A on citrate agar (pH 6.0)
CHROMATOGRAPHY		Hb X was isolated on a DEAE-cellulose column
STRUCTURE STUDIES		Tryptic digestion; separation of peptides by reversed phase HPLC; amino acid analysis; sequencing
DNA ANALYSES		Not reported; presumed mutation AAG->AAC or AAT; alpha2 or alpha1
FUNCTIONAL STUDIES		Not reported
STABILITY		Not reported
OCCURRENCE		Found in a 15-year-old Black female
OTHER INFORMATION		Quantity in the heterozygote 23.8%

REFERENCES
1.		Webber, B.B., Lam, H., Wilson, J.B., and Huisman, T.H.J.: Hemoglobin, 7:257, 1983.
2.		Shimasaki, S., Iuchi, I., Hidaka, K., and Mizuta, W.: Jpn. J. Hum. Genet., 28:127, 1983.

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This material is from the book A Syllabus of Human Hemoglobin Variants (1996) by Titus H.J. Huisman, Marianne F.H. Carver, and Georgi D. Efremov, published by The Sickle Cell Anemia Foundation in Augusta, GA, USA. Copyright © 1996 by Titus H.J. Huisman. All rights reserved. Neither this work nor any part may be reproduced or transmitted in any form or by any means, electronic or mechanical, microfilming and recording, or by any information storage and retrieval systems, without written permission.