Hb Aichi | alpha50(CE8)His->Arg |
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CONTACT | External | ||
HEMATOLOGY | Normal in the heterozygote | ||
ELECTROPHORESIS | Hb X and Hb A can best be separated by IEF; Hb X moves slower than Hb A | ||
CHROMATOGRAPHY | Not reported | ||
STRUCTURE STUDIES | Tryptic digestion; separation of peptides by fingerprinting; amino acid analysis | ||
DNA ANALYSES | Not reported; presumed mutation CAC->CGC; alpha2 or alpha1 | ||
FUNCTIONAL STUDIES | Normal oxygen affinity | ||
STABILITY | Slightly unstable | ||
OCCURRENCE | Found in a Japanese family | ||
OTHER INFORMATION | Quantity in heterozygotes 21-22% |
REFERENCES | |||
1. | Harano, T., Harano, K., Shibata, S., Ueda, S., Mori, H., and Seki, M.: FEBS Lett., 169:297, 1984. |