Hb F-Pendergrass | Agamma36(C2)Pro->Arg |
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ELECTROPHORESIS | Hb FX moves about like Hb S at alkaline pH | ||
IEF | Not reported | ||
CHROMATOGRAPHY | Hb FX separates from Hb A and Hb F by DEAE-cellulose chromatography | ||
CHAIN SEPARATION | No data reported | ||
STRUCTURE STUDIES | Tryptic digestion of gammaX chain; separation of peptides by reversed phase HPLC; amino acid analysis | ||
DNA ANALYSES | Not reported; presumed mutation CCA->CGA at codon 36 | ||
NOTES | Found in a Caucasian newborn; Hb FX 6.7% of total Hb or 8.5% of total Hb F |
REFERENCES | |||
1. | Chen, S.S., Wilson, J.B., and Huisman, T.H.J.: Hemoglobin, 9:73, 1985. |