Hb F-Bonaire-GA Agamma39(C5)Gln->Arg
ELECTROPHORESIS Hb FX moves between Hb S and Hb C at alkaline pH
IEF Not reported
CHROMATOGRAPHY Hb FX readily separates from Hb F and Hb A by DEAE-cellulose chromatography
STRUCTURE STUDIES Tryptic digestion of gamma-FX chain; separation of peptides by reversed phase HPLC; amino acid analysis; sequencing
DNA ANALYSES Not reported; presumed mutation CAG->CGG at codon 39
NOTES Found in a Caucasian-Vietnamese baby; Hb FX 8.3% of total Hb or 9.8% of total Hb F
1. Nakatsuji, T., Headlee, M., Lam, H., Wilson, J.B., and Huisman, T.H.J.: Hemoglobin, 6:599, 1982.

This material is from the book A Syllabus of Human Hemoglobin Variants (1996) by Titus H.J. Huisman, Marianne F.H. Carver, and Georgi D. Efremov, published by The Sickle Cell Anemia Foundation in Augusta, GA, USA. Copyright © 1996 by Titus H.J. Huisman. All rights reserved. Neither this work nor any part may be reproduced or transmitted in any form or by any means, electronic or mechanical, microfilming and recording, or by any information storage and retrieval systems, without written permission.